Selank

Selank Peptide Structure

Authoritative source：PubChem

Selank peptide is a synthetic peptide that has been gaining popularity in recent years due to its numerous health benefits. With all the talk of people using Selank peptide recently, many are still wondering about the benefits of it and what it actually does. We’ll be going over the numerous potential health benefits of this Selank peptide and nootropic.

What Is Selank Peptide And Tuftsin?

Selank for sale is well know as the Natural Xanax and Anxiolytic Peptide. Selank is a nootropic, and Selank is a synthetic peptide derived from the human peptide tuftsin, a tetrapetide associated with the immune system. Since nootropic selank peptide is synthesized based on the structure of tuftsin, it’s technically referred to as a “synthetic analog” of tuftsin. So before to know what is Selank peptide, let’s see what is “tuftsin,” and why do scientists synthesize selank based on it.[1][2]

-What Is Tuftsin?

Tuftsin was first discovered in 1983, is an endogenous peptide which is a naturally occurring compound in the human body, that also shows anxiolytic effects. Tuftsin peptide was named after “Tufts University”.

Usually, the amount and concentration of the natural tuftsin peptide in our bodies are minimal. However, when the body is under stress, it releases more tuftsin to settle down the stressor and calm the body.

Unfortunately, the lifespan of tuftsin is very short, no more than several minutes, meaning its effects on our nervous system is transient. To prolong the effects of tuftsin, scientists are working on another synthetic peptide that mimics it but with higher stability. That is Selank peptide.[3]

-What Is Selank Peptide?

Peptide Selank online(Russian: Cеланк) is a nootropic, anxiolytic peptide based drug, it was produced by the Institute of Molecular Genetics of the Russian academy of sciences (IMG RAS). Peptide Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is a synthetic analogue of a human tetrapeptide tuftsin.

Selank peptide is considered to be an anxiolytic or a substance with anti-anxiety effect. Meantime, Selank as is a synthetic analog of the endogenously produced peptide Tuftsin, is known to be capable of improving and positively altering the immune system, which classifies selank as immunomodulatory.[4]

Selank Peptide History/Background

Bulk Selank peptide is a synthetic peptide that is popular in the nootropic market in recent years due to its numerous health benefits. Bulk Selank was developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. The Russian name of Selank peptide is Cеланк.

Peptide Selank powder is a synthetic peptide derived from tuftsin that was first discovered in 1983, and named after “Tufts University”.[5][6]

How Does Peptide Selank Work丨Mechanism Of Action Of Selank Nootropic

Clinical studies have shown the similarity of the spectrum of physiological effects of Selank and classical benzodiazepines, such as diazepam and phenazepam. These data suggest that there is a similar basis of their mechanism of action. Here is how does the Selank peptide work.

Selank working method 1: Immunomodulatory

From a purely pharmacological standpoint, peptpide selank mimics a lot of the effects of tuftsin which is the endogenous peptide it is based upon. These effects include the balance of T helper cells and the modulation of the expression of Interleukin-6.

Additionally, there is evidence that suggests nootropic selank may modulate the expression of brain-derived neurotropic factor (BDNF).[7][8]

Selank working method 2: Serotonin, Noradrenaline and Dopamine Modulation

Peptide Selank’s mechanism of action is  suspected to be related to the increase of serotonin. Serotonin influence’s appetite, supports a positive mood, and regulates the sleep and wake cycle. It is also well established that a serotonin deficient state can lead to depression, difficulty sleeping, and lack of an appetite.

A study on mice to unveil the effects of selank on neurotransmitter monomines and their metabolites showed significant differences in the content of dopamine, serotonin, norepinephrine, and in the levels of their hypothalamus, hippocampus, and frontal cortex.  Further research supports selank’s serotonin raising ability.[9]

Selank and tuftsin were also shown to support serotonin levels despite rats being pre-treated with the serotonin synthesis inhibitor p-chlorophenylalanine. Serotonin metabolism was enhanced within 30 minutes of selank administration, however tuftsin was unable to raise 5-HT levels.

Rodents exposed to 6-hydroxydopamine, a neurotoxin which damages the catecholaminergic system, had cognitive processes restored with selank.

Top 10 Benefits Of Selank Peptide Use

Clinical studies have shown that Selank peptide for sale online had an anxiolytic effect comparable to that of classical benzodiazepine drugs, which can enhance the inhibitory effect of GABA by allosteric modulation of GABAA receptors. These data suggest that the molecular mechanism of the effect of peptide Selank may also be related to its ability to affect the performance of the GABAergic system. Here are top 10 benefits of Selank peptide for sale:

1. Set Yourself Free From Anxiety丨Improve Anxiety

Bulk Selank peptide for sale has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and anti-stress drug that relieves aggression and fear reaction in different animal species.

One study involving 62 patients with generalised anxiety disorder (GAD) sought to compare selank lyophilized powder to a benzodiazepine treatment. 30 patients were treated with selank, while 32 with benzodiazepines, Remarkably, efficacy for both drugs was similar, however researchers noted selank carried anti-fatigue effects. Full details on this study are difficult to obtain, as it was conducted in Russia and only the abstract has been indexed in pubmed.

Another study tested the immunomodulatory effects of selank, given that it’s endogenous “cousin” peptide, tuftsin, is primarily related to immune function. Selank was administered to patients with generalised anxiety disorder for 14 days, after which, it was noted that selank supressed IL-6 levels of patients with depression, while leaving healthy control subjects unaffected.  T-helper cell (Th1/Th2) cytokines were also modulated in patients with GAD.

2. Improve Your Learning Skills

Selank peptide also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity.The peptide Selank has been labeled as an “anti-anxiety” peptide and has also shown improvement in learning, memory, cognition, depression, weakness, and overall energy.  

3. Possess Neuroprotective Properties

Selank Peptide has been shown to possess neuroprotective properties, meaning it can protect brain cells from oxidative stress and other harmful factors. This may be beneficial in the treatment of neurodegenerative diseases and in promoting overall brain health.

4. Enhances Your Memory

Selank peptide was originally developed as an anti-anxiety medication, Selank has since been used for a wide range of conditions. There are studies show that petpide Selank can may help to enhance memory.[10]

5. Help With Recovery From Brain Damage

Studies show that Selank peptide for sale may help with brain damage recovery as it also increases blood flow to the brain. Peptide Selank may also increase BDNF (brain-derived neurotrophic factor), an important brain-growth compound.

6. Antioxidant Effects

Studies show that Selank peptide increases the intracellular levels of antioxidants in the liver.

7. Weight Control

Studies show that Selank peptide may help topPrevent weight gain and reduce cholesterol.

8. Release Stress

Studies show that one of the primary benefits of using selank peptide is its ability to reduce stress levels. By stimulating GABA receptors, selank peptide may promote relaxation and calmness while reducing tension and restlessness. Additionally, it helps regulate cortisol levels in the body, which are responsible for inducing stress responses.

As a result, use Selank peptide can experience improved mental clarity and focus while feeling more relaxed overall.

9. Sobriety

Studies show that Selank peptide may decreases alcohol-withdrawal-related anxiety, thus helping to quit drinking.[11]

10. Regulate Immunity

Studies show that Selank peptide strengthens immune function by increasing inflammatory proteins to help fight infections.

How To Use Nootropic Selank Peptide,Oral? Inject？

The common seen use method of Selank peptide is nasal spray or injection. However, a compounding pharmacy can assist with providing you Selank peptide in different forms, whether it’d be a pill or any other type of Selank.

A peptide manufacturer specializes in providing different peptides with different functions like anxiety, depression, erectile dysfunction, bodybuilding, weight loss.

If you want to buy Selank peptide from a compounding pharmacy, compounding pharmacists then synthesize the medications to meet the patient’s specific needs. If the patient responds better to an oral pill than an injection, they may synthesize the drug for them if the medication doesn’t come as a pill. Selank powder is the base ingredient that use to synthesis oral or inject Selank peptide.[12]

How Should I Take The Selank丨Peptide Selank Dosage

Selank peptide is a nasal spray or oral that can be administered daily or as needed. It is often combined with another nasal spary peptide called Semax. 

According to research, the peptide selank, when administered intranasally, regulates BDNF expression in the rat hippocampus. Specifically, at doses of 250 or 500 µg/kg body weight, selank significantly increased BDNF protein levels in the hippocampus 3 hours after administration.

You can ask your doctor or family health manager for more information about the detailed dosage of Selank peptide dose.

Why Selank Is Often Use With Semax Together丨Selank And Semax Combination

Peptide Semax is a drug which is used mostly in Russia for a broad range of conditions but predominantly for its purported nootropic, neuroprotective, and neurorestorative properties.

Both Peptide Selank and Semax act as Melanocortin Stimulating Hormone-like Peptides within the brain to initiate wide ranging effects related to brain activity and fitness.[13]

Selank is often prescribed for its anxiolytic properties, immune improvement, gastric protection, and with opioid and alcohol withdrawal/ dependence. While Semax has been prescribed for anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal and even chronic diseases such as ALS, Parkinson’s Disease, and Alzheimer’s.

As a combination, use Selank and Semax together has applications in improving learning processes, exploratory behavior, regeneration and development, nociceptive and inflammatory processes, accelerate nerve regeneration and improve neuromuscular performance and overall neural health.[14]

Is It Safe To Use Selank?丨Side Effects Of Selank Peptide

As people become more concerned about their own health, Selank is becoming more and more talked about due to its multiple health benefits. Is it safe to use Selank peptide? Is there any side effects of Selank peptide for sale?

Yes, it is safe to use Selank peptide. Selank by itself has traditionally been prescribed for anxiety and depression. Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and anti-stress medication.

Peptide Selank has an advantage over traditional anxiety treatments, such as benzodiazepines, as it has no sedating or negative cognitive side effects and no associated addiction or withdrawal problems.

More Research Of Selank Peptide丨Selank And Serotonin

Do you know a hormone called “serotonin” ?

Serotonin is a neurotransmitter that acts as a hormone, functioning by carrying messages between our nerve cells and throughout the body. Because serotonin, we can control our mood, appetite, sleep, memory, learning, and social behavior.

Although 90% of serotonin is found in the gastrointestinal tract and only 10% is produced in our brain, this substance is a primary factor in depression and anxiety. Because serotonin is too important, therefore, a lack of serotonin may lead to psychological problems.

Studies show that Selank increase serotonin levels by correcting any decrease in serotonin metabolism.

According to a study, selank enhances the metabolism of serotonin in the brain stem 30 minutes after injection to animal subjects. This effect of selank is superior to tuftsin, as the latter doesn’t cause any changes in serotonin levels.

Where To Buy The Pure Peptide Selank Lyophilized Powder

Are you looking for a reliable and credible source to purchase Selank? Wondering where to buy the pure Selank peptide? Polypeptide.ltd is a peptides manufacturer where you can buy the Selank in both powder form and Lyophilized Powder in vial form, from different standard like 5mg, 10mg…

Selank Peptide therapy is a cutting-edge medical treatment that has gained popularity recently for its numerous health benefits. Selank is a synthetic analogue of the immunomodulatory peptide tuftsin; as such, it mimics many of its effects. It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cell cytokines. It has been shown to influence the concentration of monoamine neurotransmitters and induce metabolism of serotonin. Selank peptide has also been found to rapidly elevate the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of rats.

Selank, as well as a related peptide drug Semax, have been found to inhibit enzymes involved in the degradation of enkephalins and other endogenous regulatory peptides, and this action may be involved in their effects. It has also been found to affect the activity of carboxypeptidase H and phenylmethylsulfonylfluoride-inhibited carboxypeptidase in rat nervous system tissue.

While peptide therapy is very safe, it is recommended to take the prescribed amount from your primary care physician or doctor. A doctor or physician will be able to tell you whether Selank is the best option for your health needs.[15]

Selank peptide has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species

Selank peptide is gaining popularity due to the safety of peptide therapy and its multiple health benefits. Are you looking for buying Selank peptide? Wondering where to buy the best quality Selank peptide?  Here is the place where you are.

As the best Selank peptide manufacturer, Polypeptide.ltd is not only supply the peptide Selank in powder form but provide the customized standard easy use vial form, from 5mg, 10mg.. different package.

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Polypeptide.ltd as a peptide factory, is the best place where you can buy Selank peptide in compeptitive price, from small to bulk quantity. Click and make a contact, you will get all the details. Before buy Selank peptide, you may curious:

What Are The Advantages If Buy Selank From Polypeptide.ltd?

• Competitive Factory Price-Factory direct sales, No middlemen make a difference.
• Customization Service-Product specifications can be customized to create your own peptide brand.
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• Fast Shipping-Professional logistics customization solutions, on-time delivery.
• Easy Payment-Payment methods that are diverse.
• 365/24/7 Service-High quality pre-sales and after-sales service, followed by product and order details consultation.

How To Get The Quick Price Of Selank Petide Online?

• Visit professional Selank supplier Polypeptide.ltd, choose the Selank petide that you want to buy.
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• The customer service will reply you in 12 hours once received your message, then talk in details about buy Selank peptide.

Does Polypeptide.ltd Support The Free Sample Of Selank Powder?

It depends, different products with different policy, please check it with our customer service. Most of products can be accepted for sample.

Can I Appoint The Selank Colour When Buy Selank vials?

YES! Polypeptide.ltd as peptide manufacturer, provide colour customization of Selank, easy to help you to build your Selank peptide brand.

Can I Appoint The Products Standard When Buy  Selank From Polypeptide.ltd?

YES! As one of the best Selank manufacturer, Polypeptide.ltd not only provide the standard specification of Selank in 5mg, 10mg, but support standard customization. Provide the best support to build your own Selank brand.

Can I Buy Selank In Pure Powder Form From Polypeptide.ltd?

YES! Selank powder is the base that use for Selank lyophilized powder manufacture. Polypeptide.ltd provide Selank in both of pure powder form and semi-finished vial form.

Can I Buy Discount Selank Powder From Polypeptide.ltd?

YES! Our factory produce high quality Selank powder in term and keep Selank powder in stock. You can buy high quality Selank powder in bulk. During promotion sale, you can buy Selank peptide by lower price. You can keep touch with our customer manager and they will update the latest bulk Selank price for you in time.

What Does Selank Peptide Do For You?

Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species (Kozlovskii and Danchev, 2002; Sollertinskaya et al., 2008; Semenova et al., 2010)

How does Selank work in the brain?

Selank peptide mechanism of action: Selank primarily works by regulating neurotransmitter levels in the brain, including serotonin, dopamine, and gamma-aminobutyric acid (GABA). These neurotransmitters play a crucial role in mood regulation, anxiety, and other cognitive processes.

Does Selank have side effects?

Although Selank peptide’s actions are similar to those of tranquilizers or traditional anxiety treatments, such as xanax and benzodiazepines, Selank has no sedating or negative cognitive side effects and has no associated addiction or withdrawal problems.

Does Semax increase dopamine?

The synthetic peptide semax (a fragment of ACTH 4-7 Pro-Gly-Pro) enhances the release of extracell dopamine (DA) induced by D-amphetamine (5 mg/kg) in the striatum of Spraig-Dowley (SD) rats and increases the locomotor activity stimulated by D-amphetamine (2 mg/kg) in C57/BL6 mice.

Can I Take Selank Peptide Oral?

Yes, there are 3 possible ways to administer the Selank peptide therapy to patients: injection, nasal spray, or oral administration.

How long does it take for Selank to work?

We found positive correlation between the changes in genes expression within 1 h after administration of Selank or GABA. Our results showed that Selank caused a number of alterations in the expression of genes involved in neurotransmission.

Does Selank cause weight gain?

Experiments have also demonstrated the effectiveness of Selank in preventing the accumulation of body fat (i.e., weight gain) with simultaneous activation of the functional state of the anticoagulation system in development of the metabolic syndrome.